Pharmacological and Phytochemical Screening of Annona Squamosa L. for Anti-Ulcer Activity

Abstract

This study investigates the anti-ulcer activity of the aqueous extract of Annona squamosa L. against
Aspirin induced ulcer. Gastric ulcer disease is caused byan imbalance between mucosal defense factors
and injurious factors, such as acid and pepsin. Ulcers caused by pylorus ligation result from increased
gastric acid and pepsin accumulation, leading to auto digestion of gastric mucosa and breaking down the
gastric mucosal barrier. NSAIDs are frequently associated with peptic ulcers.