Pharmacological Treatment of Postoperative Sleep Disorders in the First Two Nights. Examination in Detail

Abstract

The restorative benefits of sleep are especially important to take into account in the immediate postoperative period. Acute sleep 
disturbances after surgery are seldom discussed in the medical literature. Most pharmaceutical treatments include the use of 
benzodiazepines, however because of their potential for adverse effects, it is highly advised that a tailored approach be used. The 
purpose of this narrative review was to analyze effective pharmacological treatments for acute sleep problems in the first 48 hours 
after surgery in patients who had planned medical operations. A narrative search was performed in the databases of Embase, PubMed, 
and Cochrane. No studies other than randomized controlled trials and systematic reviews were examined.
The effectiveness of pharmaceutical therapies for acute sleep problems, the methods of administration, and the effect on postoperative 
descents were the major outcomes. The original search turned up 271 papers, however only 7 were suitable for inclusion. 
Pharmacological treatments like 5mg of Zolpidem before bed and >900mg of Gabapentin are often used. The first postoperative phase 
is crucial for treating these diseases, and it has been found that Dexmedetomidine IV infusion at a dosage of 0.05 mcg/kg/h is 
effective.